DataCœur Research Team, ETHICS Laboratory – EA 7446
Accredited University Research Unit
Coordinated by Sylvestre Maréchaux,
The DataCœur team develops recognized expertise in the study and management of cardiac pathologies, with a particular focus on:
Valvular heart diseases, Heart failure and resynchronization, Arrhythmias and cardiac pacing.
Through innovative research, combining multi-modal imaging, electrophysiology, and clinical approaches, our objective is to improve diagnosis and treatments in order to optimize patient management.
The DataCœur research team possesses expertise in the field of cardiac valvular diseases, cardiac arrhythmias and pacing, heart failure, and resynchronization.
Research Team: Sylvestre Maréchaux, Alban Baillez, Dimitri Bellevre, Tanguy Blaire, Alexandre Altes, Nicolas Thellier, Louis Rousselet, Marc-Antoine Delbarre, Lorette Averlant, Aymeric Menet.
Research Professionals Team: Valentine Pecriaux, Achwaq Lebouazda, our IPA team, our research intern teams.
Contributors: open to anyone actively involved in research. Membership is granted upon request from contributors to the research team, accompanied by a summary of their research contribution.
Our Research Areas
VALVULAR HEART DISEASES
For several years, the team has been committed to identifying and evaluating criteria derived from multimodal cardiac imaging (echocardiography, MRI, CT scan, nuclear imaging).
Our work focuses on large cohorts of patients with: aortic stenosis, mitral regurgitation, and aortic regurgitation.
In collaboration with internationally renowned centers, we aim to refine the diagnostic approach to better personalize patient management.
ARRHYTHMIAS AND CARDIAC PACING
The DataCœur team also conducts research on:
the treatment of arrhythmias by cardiac catheterization and physiological cardiac pacing.
Our work relies on:
national multicenter cohorts, health databases, and original local projects.
All these research efforts aim at a central objective: to improve the quality and precision of patient care.
HEART FAILURE AND RESYNCHRONIZATION
For over 15 years, we have been conducting in-depth research on the electrical and mechanical synchronization of the heart in heart failure.
Thanks to close collaboration between echocardiography and electrophysiology laboratories, we have been able to:
identify the link between electrical activation and mechanical synchronization and improve the selection of patients eligible for cardiac resynchronization therapy by pacemaker.
Our echocardiography laboratories are certified by the European Society of Cardiology, a guarantee of quality and involvement in research and education.
RESEARCH IN THE THEME OF INTERNATIONAL DATABASES
Randomized blinded clinical trials are the gold standard for evaluating the efficacy and tolerability of treatments.
However, they have limitations, particularly in terms of representativeness.
The DATACARD team works on national health databases using artificial intelligence algorithms to achieve near-completeness of data.
This work is carried out in partnership with the INSERM UMS 11 team from Paul Brousse Hospital in Paris, the startup Implicity, and the ReDSiam network on cardiac rhythmology topics.
AMYLOIDOSIS