Sylvestre Marechaux -

Sylvestre Marechaux

Professor Sylvestre Maréchaux is a renowned academic cardiologist, specialized in valvular heart disease, cardiomyopathies, and heart failure. A graduate of the Faculty of Medicine in Lille, he defended his doctoral thesis in 2007, focusing on the contribution of biomarkers to the diagnosis of aortic stenosis. He subsequently earned an Inter-University Diploma in cardiovascular imaging (MRI, CT) in 2010, and in the same year obtained his Habilitation to Supervise Research (HDR).

He is currently Head of the Cardiology Department at the Groupe Hospitalier de l’Institut Catholique de Lille (GHICL) and Director of DATA-CŒUR. A Professor at the Faculty of Medicine, Midwifery and Health Sciences of Lille, he also serves as Vice-Dean for Research Promotion. He is Treasurer of the Cardiovascular Imaging Section of the French Society of Cardiology and a member of the Education Committee of the European Association of Cardiovascular Imaging (EACVI) in Echocardiography.

His scientific activity focuses on advanced cardiac imaging (echocardiography, MRI) and the functional and prognostic assessment of cardiovascular diseases. He is the author of numerous publications in international peer-reviewed journals and is actively involved in translational research projects. He regularly supervises doctoral theses and the work of young researchers, contributing to the training of a new generation of clinician-scientists.

At the head of his research team, he is dedicated to advancing the understanding of complex cardiovascular diseases, integrating technological innovations and personalized approaches to medicine.

Publications

Altes A, Levy F, Hanet V, De Azevedo D, Krug P, Iacuzio L, Dommerc C, Silvestri V, Toledano M, Delelis F, Vancraeynest D, Pasquet A, Maréchaux S,
Gerber BL. Impact of Sex on Severity Assessment and Cardiac Remodeling in Primary Mitral Regurgitation. JACC Adv. 2024 Jun 4;3(7):101023. doi: 10.1016/j.jacadv.2024.101023. PMID: 39130021; PMCID: PMC11312794.

Vermes E, Iacuzio L, Maréchaux S, Levy F, Loardi C, Tribouilloy C. Is there a role for cardiovascular magnetic resonance imaging in the assessment of biological aortic valves? Front Cardiovasc Med. 2023 Dec 6;10:1250576. doi: 10.3389/fcvm.2023.1250576. PMID: 38124892; PMCID: PMC10730731.

Thellier N, Altes A, Rietz M, Menet A, Layec J, Outteryck F, Appert L, Tribouilloy C, Maréchaux S. Additive Prognostic Value of Left Ventricular
Dispersion and Deformation in Patients With Severe Aortic Stenosis. JACC Cardiovasc Imaging. 2024 Mar;17(3):235-245. doi: 10.1016/j.jcmg.2023.09.010. Epub 2023 Nov 8. PMID: 37943232.

Bohbot Y, Hucleux E, Rusinaru D, Diouf M, Levy F, Altes A, Maréchaux S, Tribouilloy C. Right Ventricle to Pulmonary Artery Coupling in Severe Aortic
Stenosis With Preserved Ejection Fraction. JACC Cardiovasc Imaging. 2024 Feb;17(2):220-222. doi: 10.1016/j.jcmg.2023.08.017. Epub 2023 Oct 18. PMID: 37855799.

Bernard J, Yanamala N, Shah R, Seetharam K, Altes A, Dupuis M, Toubal O, Mahjoub H, Dumortier H, Tartar J, Salaun E, O’Connor K, Bernier M, Beaudoin J, Côté N, Vincentelli A, LeVen F, Maréchaux S, Pibarot P, Sengupta PP. Integrating Echocardiography Parameters With Explainable Artificial Intelligence for Data- Driven Clustering of Primary Mitral Regurgitation Phenotypes. JACC Cardiovasc Imaging. 2023 Oct;16(10):1253-1267. doi: 10.1016/j.jcmg.2023.02.016. Epub 2023 May 10. PMID: 37178071.

Layec J, Decroocq M, Delelis F, Appert L, Guyomar Y, Riolet C, Dumortier H, Mailliet A, Tribouilloy C, Maréchaux S, Menet A. Dyssynchrony and Response to Cardiac Resynchronization Therapy in Heart Failure Patients With Unfavorable Electrical Characteristics. JACC Cardiovasc Imaging. 2023 Jul;16(7):873-884. doi: 10.1016/j.jcmg.2022.12.023. Epub 2023 Mar 8. PMID: 37038875.

Altes A, Vermes E, Levy F, Vancraeynest D, Pasquet A, Vincentelli A, Gerber BL, Tribouilloy C, Maréchaux S. Quantification of primary mitral regurgitation by echocardiography: A practical appraisal. Front Cardiovasc Med. 2023 Mar 10;10:1107724. doi: 10.3389/fcvm.2023.1107724. PMID: 36970355; PMCID: PMC10036770.

Vermes E, Altes A, Iacuzio L, Levy F, Bohbot Y, Renard C, Grigioni F, Maréchaux S, Tribouilloy C. The evolving role of cardiovascular magnetic resonance in the assessment of mitral valve prolapse. Front Cardiovasc Med. 2023 Mar 3;10:1093060. doi: 10.3389/fcvm.2023.1093060. PMID: 36937904; PMCID: PMC10020178.

Altes A, Bernard J, Dumortier H, Dupuis M, Toubal O, Mahjoub H, Tartar J, Côté N, Clavel MA, O’Connor K, Bernier M, Beaudoin J, Vincentelli A, Pibarot P, Maréchaux S. Clinical significance of myocardial contraction fraction in significant primary mitral regurgitation. Arch Cardiovasc Dis. 2023 Mar;116(3):151-158. doi: 10.1016/j.acvd.2023.01.004. Epub 2023 Feb 6. PMID: 36805238.

De Azevedo D, Tribouilloy C, Maréchaux S, Pouleur AC, Bohbot Y, Rusinaru D, Altes A, Thellier N, Beauloye C, Pasquet A, Gerber BL, de Kerchove L, Vanoverschelde JJ, Vancraeynest D. Prognostic Implications of Discordant Low-Gradient Severe Aortic Stenosis: Comprehensive Analysis of a Large Multicenter Registry. JACC Adv. 2023 Feb 22;2(2):100254. doi: 10.1016/j.jacadv.2023.100254. PMID: 38938309; PMCID: PMC11198650.

Thellier N, Altes A, Layec J, Castel AL, Delelis F, Hubert T, Outerryck F, Appert L, Tribouilloy C, Maréchaux S. Impact of left atrial and diastolic
ventricular dysfunction on mortality in patients with aortic stenosis. Arch Cardiovasc Dis. 2023 Mar;116(3):126-135. doi: 10.1016/j.acvd.2022.12.006. Epub 2023 Jan 20. PMID: 36739188.

Ennezat PV, Guerbaai RA, Maréchaux S, Le Jemtel TH, François P. Extent of Low-density Lipoprotein Cholesterol Reduction and All-cause and Cardiovascular Mortality Benefit: A Systematic Review and Meta-analysis. J Cardiovasc Pharmacol. 2023 Jan 1;81(1):35-44. doi: 10.1097/FJC.0000000000001345. PMID: 36027598; PMCID: PMC9812424.

Vermes E, Iacuzio L, Levy F, Bohbot Y, Renard C, Gerber B, Maréchaux S, Tribouilloy C. Role of Cardiovascular Magnetic Resonance in Native Valvular Regurgitation: A Comprehensive Review of Protocols, Grading of Severity, and Prediction of Valve Surgery. Front Cardiovasc Med. 2022 Jul 7;9:881141. doi: 10.3389/fcvm.2022.881141. PMID: 35872899; PMCID: PMC9300884.

Altes A, Bernard J, Dumortier H, Dupuis M, Toubal O, Mahjoub H, Tartar J, Côté N, Clavel MA, O’Connor K, Bernier M, Beaudoin J, Vincentelli A, Pibarot P, Maréchaux S. Significance of Left Ventricular Ejection Time in Primary Mitral Regurgitation. Am J Cardiol. 2022 Sep 1;178:97-105. doi: 10.1016/j.amjcard.2022.05.019. Epub 2022 Jun 29. PMID: 35778308.

Altes A, Levy F, Iacuzio L, Dumortier H, Toledano M, Tartar J, Tribouilloy C, Maréchaux S. Comparison of Mitral Regurgitant Volume Assessment between Proximal Flow Convergence and Volumetric Methods in Patients with Significant Primary Mitral Regurgitation: An Echocardiographic and Cardiac Magnetic Resonance Imaging Study. J Am Soc Echocardiogr. 2022 Jul;35(7):671-681. doi: 10.1016/j.echo.2022.03.005. Epub 2022 Mar 11. PMID: 35288306.

Bernard J, Altes A, Dupuis M, Toubal O, Mahjoub H, Tastet L, Côté N, Clavel MA, Dumortier H, Tartar J, O’Connor K, Bernier M, Beaudoin J, Maréchaux S, Pibarot P. Cardiac Damage Staging Classification in Asymptomatic Moderate or Severe Primary Mitral Regurgitation. Struct Heart. 2022 Mar 12;6(1):100004. doi: 10.1016/j.shj.2022.100004. PMID: 37273475; PMCID: PMC10236891 .

Kubala M, Bohbot Y, Rusinaru D, Levy F, Maréchaux S, Tribouilloy C. Refining Risk Stratification in Severe Aortic Stenosis With Left Atrial Volume and Atrial Fibrillation. JACC Cardiovasc Imaging. 2022 May;15(5):945-947. doi: 10.1016/j.jcmg.2021.11.012. Epub 2022 Jan 12. PMID: 35257679.

Leblon T, Riolet C, Ennezat P, Marechaux S. Caseous necrosis of the mitral annulus: a new feature of drug-induced valvular heart disease? Case series. Eur Heart J Case Rep. 2021 Dec 16;6(1):ytab516. doi: 10.1093/ehjcr/ytab516. PMID: 34993414; PMCID: PMC8727063.

Altes A, Thellier N, Bohbot Y, Ringle Griguer A, Verdun S, Levy F, Castel AL, Delelis F, Mailliet A, Tribouilloy C, Maréchaux S. Relationship Between the Ratio of Acceleration Time/Ejection Time and Mortality in Patients With High- Gradient Severe Aortic Stenosis. J Am Heart Assoc. 2021 Dec 7;10(23):e021873. doi: 10.1161/JAHA.121.021873. Epub 2021 Nov 30. PMID: 34845911; PMCID: PMC9075380.

Rusinaru D, Bohbot Y, Maréchaux S, Enriquez-Sarano M, Tribouilloy C. Low- flow low-gradient severe aortic stenosis: Clinical significance depends on definition. Arch Cardiovasc Dis. 2021 Aug-Sep;114(8-9):606-608. doi: 10.1016/j.acvd.2021.06.009. Epub 2021 Sep 28. PMID: 34593341.

Rusinaru D, Bohbot Y, Kubala M, Diouf M, Altes A, Pasquet A, Maréchaux S, Vanoverschelde JL, Tribouilloy C. Myocardial Contraction Fraction for Risk Stratification in Low-Gradient Aortic Stenosis With Preserved Ejection Fraction. Circ Cardiovasc Imaging. 2021 Aug;14(8):e012257. doi: 10.1161/CIRCIMAGING.120.012257. Epub 2021 Aug 17. PMID: 34403263.

Levy F, Iacuzio L, Marechaux S, Civaia F, Dommerc C, Wautot F, Tribouilloy C, Eker A. Influence of Prolapse Volume in Mitral Valve Prolapse. Am J Cardiol.
2021 Oct 15;157:64-70. doi: 10.1016/j.amjcard.2021.07.019. Epub 2021 Aug 10. PMID: 34389154.

Riolet C, Menet A, Mailliet A, Binda C, Altes A, Appert L, Castel AL, Delelis F, Viart G, Guyomar Y, Le Goffic C, Decroocq M, Ennezat PV, Graux P, Tribouilloy C, Marechaux S. Clinical Significance of Global Wasted Work in Patients with Heart Failure Receiving Cardiac Resynchronization Therapy. J Am Soc Echocardiogr. 2021 Sep;34(9):976-986. doi: 10.1016/j.echo.2021.06.008. Epub 2021 Jun 19. PMID: 34157400.

Debry N, Altes A, Vincent F, Delhaye C, Schurtz G, Nedjari F, Legros G, Porouchani S, Coisne A, Richardson M, Cosenza A, Verdier B, Denimal T, Pamart T, Spillemaeker H, Sylla H, Sudre A, Janah D, Aouate D, Marsou W, Appert L, Lemesle G, Labreuche J, Maréchaux S, Van Belle E. Balloon aortic valvuloplasty for severe aortic stenosis before urgent non-cardiac surgery. EuroIntervention. 2021 Oct 1;17(8):e680-e687. doi: 10.4244/EIJ-D-20-01423. PMID: 34105511; PMCID: PMC9724970.

Bohbot Y, Kubala M, Rusinaru D, Maréchaux S, Vanoverschelde JL, Tribouilloy C. Survival and Management of Patients With Discordant High-Gradient Aortic Stenosis: A Propensity-Matched Study. JACC Cardiovasc Imaging. 2021 Aug;14(8):1672-1674. doi: 10.1016/j.jcmg.2021.02.010. Epub 2021 Apr 14. PMID: 33865787.

Maréchaux S, Tribouilloy C. Acceleration Time in Aortic Stenosis: A New Life for an Old Parameter. Circ Cardiovasc Imaging. 2021 Jan;14(1):e012234. doi:
10.1161/CIRCIMAGING.120.012234. Epub 2021 Jan 19. PMID: 33461310.

Riolet C, Menet A, Verdun S, Altes A, Appert L, Guyomar Y, Delelis F, Ennezat PV, Guerbaai RA, Graux P, Tribouilloy C, Marechaux S. Clinical and
prognostic implications of phenomapping in patients with heart failure receiving cardiac resynchronization therapy. Arch Cardiovasc Dis. 2021 Mar;114(3):197-210.
doi: 10.1016/j.acvd.2020.07.004. Epub 2021 Jan 8. PMID: 33431324.

Tribouilloy C, Bohbot Y, Rusinaru D, Belkhir K, Diouf M, Altes A, Delpierre Q, Serbout S, Kubala M, Levy F, Maréchaux S, Enriquez Sarano M. Excess Mortality
and Undertreatment of Women With Severe Aortic Stenosis. J Am Heart Assoc. 2021 Jan 5;10(1):e018816. doi: 10.1161/JAHA.120.018816. Epub 2020 Dec 29. PMID:
33372529; PMCID: PMC7955469.

Rusinaru D, Bohbot Y, Djelaili F, Delpierre Q, Altes A, Serbout S, Kubala M, Maréchaux S, Tribouilloy C. Normative Reference Values of Cardiac Output by Pulsed-Wave Doppler Echocardiography in Adults. Am J Cardiol. 2021 Feb 1;140:128-133. doi: 10.1016/j.amjcard.2020.10.046. Epub 2020 Nov 2. PMID: 33144167.

Altes A, Thellier N, Rusinaru D, Marsou W, Bohbot Y, Chadha G, Leman B, Paquet P, Ennezat PV, Tribouilloy C, Maréchaux S. Dimensionless Index in Patients With Low-Gradient Severe Aortic Stenosis and Preserved Ejection Fraction. Circ Cardiovasc Imaging. 2020 Oct;13(10):e010925. doi: 10.1161/CIRCIMAGING.120.010925. Epub 2020 Oct 20. PMID: 33076698.

Thellier N, Altes A, Appert L, Binda C, Leman B, Marsou W, Debry N, Joly C, Ennezat PV, Tribouilloy C, Maréchaux S. Prognostic Importance of Left Ventricular Global Longitudinal Strain in Patients with Severe Aortic Stenosis and Preserved Ejection Fraction. J Am Soc Echocardiogr. 2020 Dec;33(12):1454-1464. doi: 10.1016/j.echo.2020.07.002. Epub 2020 Sep 9. PMID: 32919856.

Bellevre D, Bailliez A, Delelis F, Blaire T, Agostini D, Mouquet F, Maréchaux S, Manrique A. Quantitation of myocardial ^99mTc-HMDP uptake
with new SPECT/CT cadmium zinc telluride (CZT) camera in patients with transthyretin-related cardiac amyloidosis: Ready for clinical use? J Nucl Cardiol. 2022 Apr;29(2):506-514. doi: 10.1007/s12350-020-02274-2. Epub 2020 Jul 26. PMID: 32715418.

Aouate D, Menet A, Bellevre D, Damy T, Marechaux S. Deleterious effect of right ventricular pacing in patients with cardiac transthyretin amyloidosis:
potential clinical benefit of cardiac resynchronization therapy. Eur Heart J Case Rep. 2020 May 1;4(3):1-5. doi: 10.1093/ehjcr/ytaa088. PMID: 32617488;
PMCID: PMC7319833.

Altes A, Ringle A, Bohbot Y, Bouchot O, Appert L, Guerbaai RA, Gun M, Ennezat PV, Tribouilloy C, Maréchaux S. Clinical significance of energy loss
index in patients with low-gradient severe aortic stenosis and preserved ejection fraction. Eur Heart J Cardiovasc Imaging. 2020 Jun 1;21(6):608-615.
doi: 10.1093/ehjci/jeaa010. PMID: 32031603.

Bohbot Y, Guignant P, Rusinaru D, Kubala M, Maréchaux S, Tribouilloy C. Impact of Right Ventricular Systolic Dysfunction on Outcome in Aortic Stenosis.
Circ Cardiovasc Imaging. 2020 Jan;13(1):e009802. doi: 10.1161/CIRCIMAGING.119.009802. Epub 2020 Jan 21. PMID: 31959010.

Maréchaux S, Rusinaru D, Altes A, Pasquet A, Vanoverschelde JL, Tribouilloy C. Prognostic Value of Low Flow in Patients With High Transvalvular Gradient
Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction: A Multicenter Study. Circ Cardiovasc Imaging. 2019 Oct;12(10):e009299. doi:
10.1161/CIRCIMAGING.119.009299. Epub 2019 Oct 10. PMID: 31597467.

Chadha G, Bohbot Y, Rusinaru D, Maréchaux S, Tribouilloy C. Outcome of Normal-Flow Low-Gradient Severe Aortic Stenosis With Preserved Left Ventricular
Ejection Fraction: A Propensity-Matched Study. J Am Heart Assoc. 2019 Oct;8(19):e012301. doi: 10.1161/JAHA.119.012301. Epub 2019 Sep 25. PMID:
31550970; PMCID: PMC6806034 .

Altes A, Thellier N, Bohbot Y, Marsou W, Chadha G, Binda C, Ringle A, Mailliet A, Marotte N, Riolet C, Tribouilloy C, Maréchaux S. Prognostic Impact
of the Ratio of Acceleration Time to Ejection Time in Patients With Low Gradient Severe Aortic Stenosis and Preserved Ejection Fraction. Am J Cardiol. 2019 Nov
15;124(10):1594-1600. doi: 10.1016/j.amjcard.2019.07.064. Epub 2019 Aug 21. PMID: 31522771.

Altes A, Sochala M, Attias D, Dreyfus J, Bohbot Y, Toledano M, Macron L, Renard C, Chadha G, Truffier A, Guerbaai RA, Ennezat PV, Graux P, Tribouilloy C,
Maréchaux S. Correlates of the ratio of acceleration time to ejection time in patients with aortic stenosis: An echocardiographic and computed tomography
study. Arch Cardiovasc Dis. 2019 Oct;112(10):567-575. doi: 10.1016/j.acvd.2019.06.004. Epub 2019 Aug 8. PMID: 31402281.

Levy F, Iacuzio L, Schouver ED, Essayagh B, Civaia F, Dommerc C, Maréchaux S. Performance of a new fully automated transthoracic three-dimensional
echocardiographic software for quantification of left cardiac chamber size and function: Comparison with 3 Tesla cardiac magnetic resonance. J Clin Ultrasound.
2019 Nov;47(9):546-554. doi: 10.1002/jcu.22764. Epub 2019 Jul 29. PMID: 31355477.

Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula
J, Lancellotti P, Bax JJ, Généreux P, Pibarot P. Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis. J Am Coll Cardiol. 2019 Jul 30;74(4):550-563. doi: 10.1016/j.jacc.2019.04.065. PMID: 31345430.

Ennezat PV, Guerbaai RA, Maréchaux S. Studies Evaluating Statin Adherence and Outcome Should Adjust for Smoking Persistence and Antiplatelet Treatment
Discontinuation. JAMA Cardiol. 2019 Aug 1;4(8):832-833. doi: 10.1001/jamacardio.2019.1966. PMID: 31241731.

Delesalle G, Bohbot Y, Rusinaru D, Delpierre Q, Maréchaux S, Tribouilloy C. Characteristics and Prognosis of Patients With Moderate Aortic Stenosis and
Preserved Left Ventricular Ejection Fraction. J Am Heart Assoc. 2019 Mar 19;8(6):e011036. doi: 10.1161/JAHA.118.011036. PMID: 30841771; PMCID: PMC6475062.

Tribouilloy C, Rusinaru D, Bohbot Y, Maréchaux S, Vanoverschelde JL, Enriquez-Sarano M. How Should Very Severe Aortic Stenosis Be Defined in
Asymptomatic Individuals? J Am Heart Assoc. 2019 Feb 5;8(3):e011724. doi: 10.1161/JAHA.118.011724. PMID: 30712451; PMCID: PMC6405579.

Altes A, Appert L, Delelis F, Guyomar Y, Menet A, Ennezat PV, Guerbaai RA, Graux P, Tribouilloy C, Maréchaux S. Impact of Increased Right Atrial Size on
Long-Term Mortality in Patients With Heart Failure Receiving Cardiac Resynchronization Therapy. Am J Cardiol. 2019 Mar 15;123(6):936-941. doi:10.1016/j.amjcard.2018.12.015. Epub 2018 Dec 19. PMID: 30600082.

Appert L, Menet A, Altes A, Ennezat PV, Bardet-Bouchery H, Binda C, Guyomar Y, Delelis F, Castel AL, Le Goffic C, Guerbaai RA, Graux P, Tribouilloy C,
Maréchaux S. Clinical Significance of Electromechanical Dyssynchrony and QRS Narrowing in Patients With Heart Failure Receiving Cardiac Resynchronization
Therapy. Can J Cardiol. 2019 Jan;35(1):27-34. doi: 10.1016/j.cjca.2018.10.019. Epub 2018 Nov 14. PMID: 30595180.

Castel AL, Toledano M, Tribouilloy C, Delelis F, Mailliet A, Marotte N, Guerbaai RA, Levy F, Graux P, Ennezat PV, Maréchaux S. Assessment of left
ventricular size and function by 3-dimensional transthoracic echocardiography: Impact of the echocardiography platform and analysis software. Am Heart J. 2018
Aug;202:127-136. doi: 10.1016/j.ahj.2018.05.013. Epub 2018 May 27. PMID: 29935472.

Maréchaux S, Ennezat PV, Guerbaai RA, Vincentelli A, Levy F, Tribouilloy C. Dedicated heart valve networks for improving the outcome of patients with
valvular heart disease? Arch Cardiovasc Dis. 2018 Aug-Sep;111(8-9):465-469. doi: 10.1016/j.acvd.2018.03.002. Epub 2018 Apr 17. PMID: 29674156.

Levy F, Marechaux S, Iacuzio L, Schouver ED, Castel AL, Toledano M, Rusek S, Dor V, Tribouilloy C, Dreyfus G. Quantitative assessment of primary mitral
regurgitation using left ventricular volumes obtained with new automated three- dimensional transthoracic echocardiographic software: A comparison with 3-Tesla
cardiac magnetic resonance. Arch Cardiovasc Dis. 2018 Aug-Sep;111(8-9):507-517. doi: 10.1016/j.acvd.2017.10.008. Epub 2018 Mar 31. PMID: 29610031.

Ringle A, Castel AL, Le Goffic C, Delelis F, Binda C, Bohbot Y, Ennezat PV, Guerbaai RA, Levy F, Vincentelli A, Graux P, Tribouilloy C, Maréchaux S.
Prospective assessment of the frequency of low gradient severe aortic stenosis with preserved left ventricular ejection fraction: Critical impact of aortic
flow misalignment and pressure recovery phenomenon. Arch Cardiovasc Dis. 2018 Aug-Sep;111(8-9):518-527. doi: 10.1016/j.acvd.2017.11.004. Epub 2018 Feb 10.
PMID: 29439881.

Ringle Griguer A, Tribouilloy C, Truffier A, Castel AL, Delelis F, Levy F, Vincentelli A, Bohbot Y, Maréchaux S. Clinical Significance of Ejection Dynamics
Parameters in Patients with Aortic Stenosis: An Outcome Study. J Am Soc Echocardiogr. 2018 May;31(5):551-560.e2. doi: 10.1016/j.echo.2017.11.015. Epub 2018 Jan 4. PMID: 29306545.

Bohbot Y, Rusinaru D, Delpierre Q, Marechaux S, Tribouilloy C. Impact of Preoperative Left Ventricular Remodelling Patterns on Long-Term Outcome after
Aortic Valve Replacement for Severe Aortic Stenosis. Cardiology. 2018;139(2):105-109. doi: 10.1159/000484659. Epub 2018 Jan 5. PMID: 29301127.

Maréchaux S, Illman JE, Huynh J, Michelena HI, Nkomo VT, Tribouilloy C. Functional anatomy and pathophysiologic principles in mitral regurgitation: Non-
invasive assessment. Prog Cardiovasc Dis. 2017 Nov-Dec;60(3):289-304. doi: 10.1016/j.pcad.2017.11.008. Epub 2017 Dec 2. PMID: 29196230.

Gallais K, Maréchaux S, Czitrom D, Saunier C, Guerbaai RA, Castel AL, Delelis F, Tribouilloy C, Ennezat PV. Quantitative assessment of aortic
regurgitation by Doppler echocardiography: Usefulness of the comparison of aortic and pulmonary flows. Echocardiography. 2017 Dec;34(12):1872-1881. doi:
10.1111/echo.13717. Epub 2017 Nov 8. PMID: 29114924.

Levy F, Bohbot Y, Sanhadji K, Rusinaru D, Ringle A, Delpierre Q, Smaali S, Gun M, Marechaux S, Tribouilloy C. Impact of pulmonary hypertension on long-term
outcome in patients with severe aortic stenosis. Eur Heart J Cardiovasc Imaging. 2018 May 1;19(5):553-561. doi: 10.1093/ehjci/jex166. PMID: 29106494.

Binda C, Menet A, Appert L, Ennezat PV, Delelis F, Castel AL, Le Goffic C, Guyomar Y, Ringlé A, Guerbaai RA, Graux P, Tribouilloy C, Maréchaux S. Time
course of secondary mitral regurgitation in patients with heart failure receiving cardiac resynchronization therapy: Impact on long-term outcome beyond
left ventricular reverse remodelling. Arch Cardiovasc Dis. 2018 May;111(5):320-331. doi: 10.1016/j.acvd.2017.05.009. Epub 2017 Nov 6. PMID: 29102366.

Rusinaru D, Bohbot Y, Kowalski C, Ringle A, Maréchaux S, Tribouilloy C. Left Atrial Volume and Mortality in Patients With Aortic Stenosis. J Am Heart Assoc.
2017 Oct 31;6(11):e006615. doi: 10.1161/JAHA.117.006615. PMID: 29089338; PMCID: PMC5721760.

Bohbot Y, Rusinaru D, Delpierre Q, Marechaux S, Tribouilloy C. Risk Stratification of Severe Aortic Stenosis With Preserved Left Ventricular
Ejection Fraction Using Peak Aortic Jet Velocity: An Outcome Study. Circ Cardiovasc Imaging. 2017 Oct;10(10):e006760. doi: 10.1161/CIRCIMAGING.117.006760. PMID: 29021260.

Guerbaii RA, Fustier G, Ennezat PV, Ringle A, Trouillet C, Graux P, Vincentelli A, Tribouilloy C, Maréchaux S. Asymptomatic aortic stenosis: An
assessment of patients’ and of their general practitioners’ knowledge, after an indexed specialized assessment in community practice. PLoS One. 2017 Jun
5;12(6):e0178932. doi: 10.1371/journal.pone.0178932. PMID: 28582434; PMCID: PMC5459476.

Bohbot Y, Kowalski C, Rusinaru D, Ringle A, Marechaux S, Tribouilloy C. Impact of Mean Transaortic Pressure Gradient on Long-Term Outcome in Patients
With Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction. J Am Heart Assoc. 2017 Jun 1;6(6):e005850. doi: 10.1161/JAHA.117.005850. PMID:
28572283; PMCID: PMC5669186.

Bernard A, Menet A, Marechaux S, Fournet M, Schnell F, Guyomar Y, Leclercq C, Mabo P, Fauchier L, Donal E. Predicting Clinical and Echocardiographic
Response After Cardiac Resynchronization Therapy With a Score Combining Clinical, Electrocardiographic, and Echocardiographic Parameters. Am J Cardiol. 2017 Jun 1;119(11):1797-1802. doi: 10.1016/j.amjcard.2017.02.046. Epub 2017 Mar 15. PMID: 28400028.

Ringle A, Levy F, Ennezat PV, Le Goffic C, Castel AL, Delelis F, Menet A, Malaquin D, Graux P, Vincentelli A, Tribouilloy C, Maréchaux S. Relationship between exercise pressure gradient and haemodynamic progression of aortic stenosis. Arch Cardiovasc Dis. 2017 Aug-Sep;110(8-9):466-474. doi: 10.1016/j.acvd.2016.12.009. Epub 2017 Apr 7. PMID: 28395958.

Menet A, Bernard A, Tribouilloy C, Leclercq C, Gevaert C, Guyomar Y, Guerbaai RA, Delelis F, Castel AL, Graux P, Ennezat PV, Donal E, Maréchaux S.
Clinical significance of septal deformation patterns in heart failure patients receiving cardiac resynchronization therapy. Eur Heart J Cardiovasc Imaging. 2017 Dec 1;18(12):1388-1397. doi: 10.1093/ehjci/jew289. PMID: 28039208.

Tribouilloy C, Bohbot Y, Maréchaux S, Debry N, Delpierre Q, Peltier M, Diouf M, Slama M, Messika-Zeitoun D, Rusinaru D. Outcome Implication of Aortic Valve
Area Normalized to Body Size in Asymptomatic Aortic Stenosis. Circ Cardiovasc Imaging. 2016 Nov;9(11):e005121. doi: 10.1161/CIRCIMAGING.116.005121. PMID:
27903539.

Debry N, Maréchaux S, Rusinaru D, Peltier M, Messika-Zeitoun D, Menet A, Tribouilloy C. Prognostic significance of left ventricular concentric
remodelling in patients with aortic stenosis. Arch Cardiovasc Dis. 2017 Jan;110(1):26-34. doi: 10.1016/j.acvd.2016.05.010. Epub 2016 Nov 8. PMID: 27839677.

Marechaux S, Tribouilloy C. Early surgery versus watchful waiting for asymptomatic severe aortic valve stenosis: a hot topic for the past 20 years. Heart. 2017 Feb 15;103(4):258-259. doi: 10.1136/heartjnl-2016-310399. Epub 2016 Sep 23. PMID: 27664003.

Marechaux S, Menet A, Guyomar Y, Ennezat PV, Guerbaai RA, Graux P, Tribouilloy C. Role of echocardiography before cardiac resynchronization therapy: new advances and current developments. Echocardiography. 2016 Nov;33(11):1745-1752. doi: 10.1111/echo.13334. Epub 2016 Aug 25. PMID: 27562174.

Ennezat PV, Bruneval P, Czitrom D, Gueffet JP, Piriou N, Trochu JN, Patra O, Blanchard-Lemoine B, du Fretay XH, Nazeyrollas P, Assoun B, Jobic Y, Brochet E, Bogino E, Roudaut R, Augier C, Greffe L, Petit-Eisenmann H, Dambrin C, Chavanon O, Guillou L, Grisoli D, Morera P, Banfi C, Remadi JP, Fabre O, Vincentelli A, Lantuejoul S, Ikoli JF, Copin MC, Malergue MC, Maréchaux S, Tribouilloy C. Drug- induced aortic valve stenosis: An under recognized entity. Int J Cardiol. 2016 Oct 1;220:429-34. doi: 10.1016/j.ijcard.2016.06.112. Epub 2016 Jun 23. PMID: 27390966.

Maréchaux S. The Wolff-Parkinson-White Syndrome: A Test Bed for the Assessment of Myocardial Dyssynchrony? Circ Cardiovasc Imaging. 2016 Jun;9(6):e005112. doi: 10.1161/CIRCIMAGING.116.005112. PMID: 27307557.

Menet A, Bardet-Bouchery H, Guyomar Y, Graux P, Delelis F, Castel AL, Heuls S, Cuvelier E, Gevaert C, Ennezat PV, Tribouilloy C, Maréchaux S. Prognostic importance of postoperative QRS widening in patients with heart failure receiving cardiac resynchronization therapy. Heart Rhythm. 2016 Aug;13(8):1636-43. doi: 10.1016/j.hrthm.2016.05.018. Epub 2016 May 25. PMID: 27236025.

Maréchaux S, Ringle A, Rusinaru D, Debry N, Bohbot Y, Tribouilloy C. Prognostic Value of Aortic Valve Area by Doppler Echocardiography in Patients With Severe Asymptomatic Aortic Stenosis. J Am Heart Assoc. 2016 May 3;5(5):e003146. doi: 10.1161/JAHA.115.003146. PMID: 27143354; PMCID: PMC4889185.

Menet A, Guyomar Y, Ennezat PV, Graux P, Castel AL, Delelis F, Heuls S, Cuvelier E, Gevaert C, Le Goffic C, Tribouilloy C, Maréchaux S. Prognostic value of left ventricular reverse remodeling and performance improvement after cardiac resynchronization therapy: A prospective study. Int J Cardiol. 2016 Feb 1;204:6-11. doi: 10.1016/j.ijcard.2015.11.091. Epub 2015 Nov 18. PMID: 26649446.

Castel AL, Menet A, Ennezat PV, Delelis F, Le Goffic C, Binda C, Guerbaai RA, Levy F, Graux P, Tribouilloy C, Maréchaux S. Global longitudinal strain software upgrade: Implications for intervendor consistency and longitudinal imaging studies. Arch Cardiovasc Dis. 2016 Jan;109(1):22-30. doi: 10.1016/j.acvd.2015.08.006. Epub 2015 Oct 26. PMID: 26514326.

Levy F, Rusinaru D, Maréchaux S, Charles V, Peltier M, Tribouilloy C. Determinants and prognosis of atrial fibrillation in patients with aortic stenosis. Am J Cardiol. 2015 Nov 15;116(10):1541-6. doi: 10.1016/j.amjcard.2015.08.018. Epub 2015 Sep 1. PMID: 26410605.

Maréchaux S, Samson R, van Belle E, Breyne J, de Monte J, Dédrie C, Chebai N, Menet A, Banfi C, Bouabdallaoui N, Le Jemtel TH, Ennezat PV. Vascular and Microvascular Endothelial Function in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2016 Jan;22(1):3-11. doi: 10.1016/j.cardfail.2015.09.003. Epub 2015 Sep 18. PMID: 26386451.

Le Goffic C, Toledano M, Ennezat PV, Binda C, Castel AL, Delelis F, Graux P, Tribouilloy C, Maréchaux S. Quantitative Evaluation of Mitral Regurgitation Secondary to Mitral Valve Prolapse by Magnetic Resonance Imaging and Echocardiography. Am J Cardiol. 2015 Nov 1;116(9):1405-10. doi: 10.1016/j.amjcard.2015.07.064. Epub 2015 Aug 14. PMID: 26372213.

Rusinaru D, Malaquin D, Maréchaux S, Debry N, Tribouilloy C. Relation of Dimensionless Index to Long-Term Outcome in Aortic Stenosis With Preserved LVEF. JACC Cardiovasc Imaging. 2015 Jul;8(7):766-75. doi: 10.1016/j.jcmg.2015.01.023. Epub 2015 Jun 17. PMID: 26093931.

Tribouilloy C, Rusinaru D, Charles V, Boulif J, Maes F, Lévy F, Pasquet A, Maréchaux S, Vanoverschelde JL. Progression of Low-Gradient, Low-Flow, Severe Aortic Stenosis With Preserved Left Ventricular Ejection Fraction. Am J Cardiol. 2015 Aug 15;116(4):612-7. doi: 10.1016/j.amjcard.2015.05.023. Epub 2015 May 21. PMID: 26089012.

Tribouilloy C, Rusinaru D, Maréchaux S, Castel AL, Debry N, Maizel J, Mentaverri R, Kamel S, Slama M, Lévy F. Low-gradient, low-flow severe aortic stenosis with preserved left ventricular ejection fraction: characteristics, outcome, and implications for surgery. J Am Coll Cardiol. 2015 Jan 6;65(1):55-66. doi: 10.1016/j.jacc.2014.09.080. Erratum in: J Am Coll Cardiol. 2015 Mar 24;65(11):1159-60. PMID: 25572511.

Menet A, Greffe L, Ennezat PV, Delelis F, Guyomar Y, Castel AL, Guiot A, Graux P, Tribouilloy C, Marechaux S. Is mechanical dyssynchrony a therapeutic target in heart failure with preserved ejection fraction? Am Heart J. 2014 Dec;168(6):909-16.e1. doi: 10.1016/j.ahj.2014.08.004. Epub 2014 Aug 10. PMID: 25458655.

Maréchaux S, Rusinaru D, Jobic Y, Ederhy S, Donal E, Réant P, Arnalsteen E, Boulanger J, Garban T, Ennezat PV, Jeu A, Szymanski C, Tribouilloy C. Food and Drug Administration criteria for the diagnosis of drug-induced valvular heart disease in patients previously exposed to benfluorex: a prospective multicentre study. Eur Heart J Cardiovasc Imaging. 2015 Feb;16(2):158-65. doi: 10.1093/ehjci/jeu212. Epub 2014 Nov 2. PMID: 25368209.

Rusinaru D, Houpe D, Szymanski C, Lévy F, Maréchaux S, Tribouilloy C. Coronary artery disease and 10-year outcome after hospital admission for heart failure with preserved and with reduced ejection fraction. Eur J Heart Fail. 2014 Sep;16(9):967-76. doi: 10.1002/ejhf.142. Epub 2014 Aug 11. PMID: 25111982.

Maréchaux S, Le Goffic C, Ennezat PV, Semichon M, Castel AL, Delelis F, Lemahieu JM, Menet A, Graux P, Tribouilloy C. Quantitative assessment of primary mitral regurgitation using left ventricular volumes: a three-dimensional transthoracic echocardiographic pilot study. Eur Heart J Cardiovasc Imaging. 2014 Oct;15(10):1133-9. doi: 10.1093/ehjci/jeu091. Epub 2014 May 22. PMID: 24855214.

Szymanski C, Andréjak M, Peltier M, Maréchaux S, Tribouilloy C. Adverse effects of benfluorex on heart valves and pulmonary circulation. Pharmacoepidemiol Drug Saf. 2014 Jul;23(7):679-86. doi: 10.1002/pds.3642. Epub 2014 May 10. PMID: 24817577.

Brunet-Bernard A, Maréchaux S, Fauchier L, Guiot A, Fournet M, Reynaud A, Schnell F, Leclercq C, Mabo P, Donal E. Combined score using clinical, electrocardiographic, and echocardiographic parameters to predict left ventricular remodeling in patients having had cardiac resynchronization therapy six months earlier. Am J Cardiol. 2014 Jun 15;113(12):2045-51. doi: 10.1016/j.amjcard.2014.03.050. Epub 2014 Apr 2. PMID: 24793667.

Tribouilloy C, Rusinaru D, Maréchaux S. Heart failure with preserved ejection fraction: looking for new pieces of a complex puzzle. Arch Cardiovasc Dis. 2014 Feb;107(2):73-6. doi: 10.1016/j.acvd.2014.01.006. Epub 2014 Feb 20. PMID: 24559848.

Castel AL, Szymanski C, Delelis F, Levy F, Menet A, Mailliet A, Marotte N, Graux P, Tribouilloy C, Maréchaux S. Prospective comparison of speckle tracking longitudinal bidimensional strain between two vendors. Arch Cardiovasc Dis. 2014 Feb;107(2):96-104. doi: 10.1016/j.acvd.2014.01.007. Epub 2014 Feb 20. PMID: 24559847.

Maréchaux S, Guiot A, Castel AL, Guyomar Y, Semichon M, Delelis F, Heuls S, Ennezat PV, Graux P, Tribouilloy C. Relationship between two-dimensional speckle-tracking septal strain and response to cardiac resynchronization therapy in patients with left ventricular dysfunction and left bundle branch block: a prospective pilot study. J Am Soc Echocardiogr. 2014 May;27(5):501-11. doi: 10.1016/j.echo.2014.01.004. Epub 2014 Feb 8. PMID: 24513239.

Ennezat PV, Maréchaux S, Bouabdallaoui N, Le Jemtel TH. Dynamic nature of pulmonary artery systolic pressure in decompensated heart failure with preserved ejection fraction: role of functional mitral regurgitation. J Card Fail. 2013 Nov;19(11):746-52. doi: 10.1016/j.cardfail.2013.09.006. Epub 2013 Oct 4. PMID: 24263118.

Tribouilloy C, Maréchaux S, Jobic Y, Jeu A, Ederhy S, Donal E, Réant P, Arnalsteen E, Boulanger J, Garban T, Ennezat PV, Andréjak M, Rusinaru D. Frequency of drug-induced valvular heart disease in patients previously exposed to benfluorex: a multicentre prospective study. Eur Heart J. 2013 Dec;34(46):3580-7. doi: 10.1093/eurheartj/eht266. Epub 2013 Sep 6. PMID: 24014218.

Maréchaux S. Speckle-tracking strain echocardiography: any place in routine daily practice in 2014? Arch Cardiovasc Dis. 2013 Dec;106(12):629-34. doi: 10.1016/j.acvd.2013.10.001. Epub 2013 Nov 15. PMID: 24246615.

Maréchaux S, Jeu A, Jobic Y, Ederhy S, Donal E, Réant P, Abouth S, Arnasteen E, Boulanger J, Ennezat PV, Garban T, Szymanski C, Tribouilloy C. Impact of selective serotonin reuptake inhibitor therapy on heart valves in patients exposed to benfluorex: a multicentre study. Arch Cardiovasc Dis. 2013 Jun- Jul;106(6-7):349-56. doi: 10.1016/j.acvd.2013.04.006. Epub 2013 May 31. PMID: 23876809.

Ennezat PV, Maréchaux S, Pibarot P, Le Jemtel TH. Secondary mitral regurgitation in heart failure with reduced or preserved left ventricular ejection fraction. Cardiology. 2013;125(2):110-7. doi: 10.1159/000350356. Epub 2013 May 24. PMID: 23711887.

Clavel MA, Ennezat PV, Maréchaux S, Dumesnil JG, Capoulade R, Hachicha Z, Mathieu P, Bellouin A, Bergeron S, Meimoun P, Arsenault M, Le Tourneau T, Pasquet A, Couture C, Pibarot P. Stress echocardiography to assess stenosis severity and predict outcome in patients with paradoxical low-flow, low-gradient aortic stenosis and preserved LVEF. JACC Cardiovasc Imaging. 2013 Feb;6(2):175-83. doi: 10.1016/j.jcmg.2012.10.015. PMID: 23489531.

Tribouilloy C, Rusinaru D, Maréchaux S, Jeu A, Ederhy S, Donal E, Réant P, Arnalsteen E, Boulanger J, Garban T, Ennezat PV, Jobic Y. Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study. Circulation. 2012 Dec 11;126(24):2852-8. doi: 10.1161/CIRCULATIONAHA.112.111260. Epub 2012 Nov 9. PMID: 23143159.

Castel AL, Maréchaux S, Laaouaj J, Rusinaru D, Levy F, Tribouilloy C. Relationship between cutoff values of peak aortic valve velocity and those of other Doppler echocardiographic parameters of severity in patients with aortic stenosis and normal flow. Echocardiography. 2012 Nov;29(10):1150-6. doi: 10.1111/j.1540-8175.2012.01790.x. Epub 2012 Aug 3. PMID: 22862297.

Delelis F, Lacroix D, Richardson M, Klug D, Kouakam C, Brigadeau F, Guyomar Y, Graux P, Kacet S, Gautier C, Ennezat PV, Marechaux S. Two-dimensional speckle-tracking echocardiography for atrioventricular accessory pathways persistent ventricular pre-excitation despite successful radiofrequency ablation. Eur Heart J Cardiovasc Imaging. 2012 Oct;13(10):840-8. doi: 10.1093/ehjci/jes048. Epub 2012 Mar 7. PMID: 22398658.

Maréchaux S, Neicu DV, Braun S, Richardson M, Delsart P, Bouabdallaoui N, Banfi C, Gautier C, Graux P, Asseman P, Pibarot P, Le Jemtel TH, Ennezat PV; Lille HFpEF Study Group. Functional mitral regurgitation: a link to pulmonary hypertension in heart failure with preserved ejection fraction. J Card Fail. 2011 Oct;17(10):806-12. doi: 10.1016/j.cardfail.2011.05.013. Epub 2011 Jul 23. PMID: 21962418.

Maréchaux S, Hattabi M, Juthier F, Neicu DV, Richardson M, Carpentier E, Bouabdallaoui N, Delelis F, Banfi C, Breyne J, Jude B, Asseman P, Vincentelli A, Le Tourneau T, Graux P, Pibarot P, Ennezat PV. Clinical and echocardiographic correlates of plasma B-type natriuretic peptide levels in patients with aortic valve stenosis and normal left ventricular ejection fraction. Echocardiography.
2011 Aug;28(7):695-702. doi: 10.1111/j.1540-8175.2011.01418.x. Epub 2011 May 12. PMID: 21564276.

Le Ven F, Tribouilloy C, Habib G, Gueffet JP, Maréchaux S, Eicher JC, Blanchard-Lemoine B, Rousseau J, Hénon P, Jobic Y, Etienne Y. Valvular heart disease associated with benfluorex therapy: results from the French multicentre registry. Eur J Echocardiogr. 2011 Apr;12(4):265-71. doi: 10.1093/ejechocard/jeq172. Epub 2010 Dec 30. PMID: 21193484.

Maréchaux S, Six-Carpentier MM, Bouabdallaoui N, Montaigne D, Bauchart JJ, Mouquet F, Auffray JL, Le Tourneau T, Asseman P, LeJemtel TH, Ennezat PV. Prognostic importance of comorbidities in heart failure with preserved left ventricular ejection fraction. Heart Vessels. 2011 May;26(3):313-20. doi: 10.1007/s00380-010-0057-5. Epub 2010 Nov 10. PMID: 21063875.

Maréchaux S, Carpentier E, Six-Carpentier M, Asseman P, LeJemtel TH, Jude B, Pibarot P, Ennezat PV. Impact of valvuloarterial impedance on left ventricular longitudinal deformation in patients with aortic valve stenosis and preserved ejection fraction. Arch Cardiovasc Dis. 2010 Apr;103(4):227-35. doi: 10.1016/j.acvd.2010.03.003. Epub 2010 May 20. PMID: 20656633.

Maréchaux S, Lubret R, Delsart P, Hattabi M, Six-Carpentier MM, Carpentier E, Coutant V, Pinçon C, Le Tourneau T, Puisieux F, Goldstein P, Asseman P, Ennezat PV. Clinical significance of unsuspected rise in cardiac troponin in the setting of falls in older people. Emerg Med J. 2010 Jun;27(6):446-50. doi: 10.1136/emj.2009.076406. PMID: 20562140.

Maréchaux S, Hachicha Z, Bellouin A, Dumesnil JG, Meimoun P, Pasquet A, Bergeron S, Arsenault M, Le Tourneau T, Ennezat PV, Pibarot P. Usefulness of exercise-stress echocardiography for risk stratification of true asymptomatic patients with aortic valve stenosis. Eur Heart J. 2010 Jun;31(11):1390-7. doi: 10.1093/eurheartj/ehq076. Epub 2010 Mar 21. PMID: 20308041; PMCID: PMC2878968 .

Maréchaux S, Pinçon C, Poueymidanette M, Verhaeghe M, Bellouin A, Asseman P, Le Tourneau T, Lejemtel TH, Pibarot P, Ennezat PV. Elevated left atrial pressure estimated by Doppler echocardiography is a key determinant of mitral valve tenting in functional mitral regurgitation. Heart. 2010 Feb;96(4):289-97. doi: 10.1136/hrt.2009.177014. PMID: 20194204.

Maréchaux S, Terrade J, Biausque F, Lefetz Y, Deturck R, Asseman P, Le Jemtel TH, Ennezat PV. Exercise-induced functional mitral regurgitation in heart failure and preserved ejection fraction: a new entity. Eur J Echocardiogr. 2010 May;11(4):E14. doi: 10.1093/ejechocard/jep203. Epub 2009 Dec 3. PMID: 19959531.

Maréchaux S, Pinçon C, Gal B, Kouakam C, Marquié C, Lacroix D, de Groote P, Mouquet F, Le Tourneau T, Dennetière S, Guyomar Y, Solal AC, Logeart D, Asseman P, Le Jemtel TH, Ennezat PV. Functional mitral regurgitation at rest determines the acute hemodynamic response to cardiac resynchronization therapy during exercise: an acute exercise echocardiographic study. J Am Soc Echocardiogr. 2009 May;22(5):464-71. doi: 10.1016/j.echo.2009.02.002. PMID: 19307096 .

Ennezat PV, Maréchaux S, Iung B, Chauvel C, LeJemtel TH, Pibarot P. Exercise testing and exercise stress echocardiography in asymptomatic aortic
stenosis. Heart. 2009 Jun;95(11):877-84. doi: 10.1136/hrt.2008.150011. Epub 2008 Sep 23. PMID: 18812409 .

Maréchaux S, Bellouin A, Polge AS, Richardson-Lobbedez M, Lubret R, Asseman P, Berrebi A, Chauvel C, Vanoverschelde JL, Nevière R, Jude B, Deklunder G, Le Jemtel TH, Ennezat PV. Clinical value of exercise Doppler echocardiography in patients with cardiac-valvular disease. Arch Cardiovasc Dis. 2008 May;101(5):351-60. doi: 10.1016/j.acvd.2008.04.003. Epub 2008 Jun 26. PMID: 18656094 .

Marechaux S, Corseaux D, Vincentelli A, Richardson M, Ung A, Susen S, Zawadzki C, Beregi JP, Ezekowitz MD, Jude B, Le Tourneau T. Identification of tissue factor in experimental aortic valve sclerosis. Cardiovasc Pathol. 2009 Mar-Apr;18(2):67-76. doi: 10.1016/j.carpath.2007.12.014. Epub 2008 Mar 6. PMID: 18402835 .

Ennezat PV, Maréchaux S, Huerre C, Deklunder G, Asseman P, Jude B, Van Belle E, Mouquet F, Bauters C, Lamblin N, Lejemtel TH, de Groote P. Exercise does not enhance the prognostic value of Doppler echocardiography in patients with left ventricular systolic dysfunction and functional mitral regurgitation at rest. Am Heart J. 2008 Apr;155(4):752-7. doi: 10.1016/j.ahj.2007.11.022. Epub 2008 Feb 21. PMID: 18371488.

Maréchaux S, Pinçon C, Le Tourneau T, de Groote P, Huerre C, Asseman P, Van Belle E, Nevière R, Bauters C, Deklunder G, Lejemtel TH, Ennezat PV. Cardiac correlates of exercise induced pulmonary hypertension in patients with chronic heart failure due to left ventricular systolic dysfunction. Echocardiography. 2008 Apr;25(4):386-93. doi: 10.1111/j.1540-8175.2007.00616.x. Epub 2008 Jan 3. PMID: 18177381.

Maréchaux S, Ennezat PV, LeJemtel TH, Polge AS, de Groote P, Asseman P, Nevière R, Le Tourneau T, Deklunder G. Left ventricular response to exercise in aortic stenosis: an exercise echocardiographic study. Echocardiography. 2007 Oct;24(9):955-9. doi: 10.1111/j.1540-8175.2007.00501.x. PMID: 17894574.

Ennezat PV, Maréchaux S, Le Tourneau T, Lamblin N, Bauters C, Van Belle E, Gal B, Kacet S, Asseman P, Deklunder G, LeJemtel TH, de Groote P. Myocardial asynchronism is a determinant of changes in functional mitral regurgitation severity during dynamic exercise in patients with chronic heart failure due to severe left ventricular systolic dysfunction. Eur Heart J. 2006 Mar;27(6):679-83. doi: 10.1093/eurheartj/ehi682. Epub 2005 Dec 16. PMID: 16361325.

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